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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ef3246006541a9a95218c33d9175899c65d70e742122a47e4aa4263ca90ad606' 
  AND token = 'rUSsaIuhBFDX+4o28rkYV71gtIA7dfBhUvCfyxPITlk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00043

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}