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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '073eb97081211872c0218a733d3e04a7f32e18d688d7c80e42f3c682fd824beb' 
  AND token = 'NULgLerkL2vFHidispHqYcirN6OeIFbCowYGoviuhyU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00121

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}