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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c0b12c003cfffd3363bcefc16a221939d67bb2940009fbd9aedcd98180db29b0' 
  AND token = 'tNu1JxmLioLn5rGRLSRjK7gjJzw+3HTdxG4sbESimLA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}