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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '51c3c3e356843294089b45c2ef93e7d51dd5e45601a73c18bd3bfa024fe18a26' 
  AND token = '/LBZ1IhvdO1j607flxqKpoWp1lCgUbci1P8LKLaFehU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}