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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f9e277db39050e06ffc1ea99801f8275443f8d6aa9f499d71a0c7f6e14af5a15' 
  AND token = 'V2Zpu0K67/rW+kV4gdPNxhbvpEyrWos3DfQDwHM1ZGw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}