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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f115df12faed2753c00319030c94e96064a2f3d7c5aa66d6c527e3ddcce19141' 
  AND token = 'MSwm8285UQ1c7rmwPf0wRIkrEHDb5+NPPRs7wQslvsg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}