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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '41391e0ca5a42e62770a7be8d12c3ec55f0944ab01e1700abc64e09e47e83e68' 
  AND token = 'Can/CwaUYEL4Tn4hEWmdXVbQLghHicE5Bm+1EKdmBFI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}