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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9e8de70039eb9fd87e6182c2aee8dcc88e39813b6a80efe74110946a895a2824' 
  AND token = 'mopTwD2D6mIQH4MMHJGSNW4e35U3jmDqr9M5ygX7LCQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}