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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5ae219e6302141b916412d11653b19a6f050a40ef2b70437eddfb42cff85365d' 
  AND token = 'avGyFFOd2vf2Bh2y7S5rpms5TQ20y/R1VB8Rm5PjULQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}