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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f45559934f3c95019afc18ea114a0cd335f370e0ca7d6b71b13be94b8c0a901a' 
  AND token = 'Qbxj6swcOMogeVYYjRvAyCpC0vJioMLyE+HpmxA8UTQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}