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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2a418695fc6a09d45c2aa51016ef7e41c56c18b131641386aa65e0b88c839cc1' 
  AND token = 'FnbmcEP4BAGl9xN35KfKexLDVyDG4MfZCYNMgE+GU1A=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}