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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1864a078c638d7ef0240562f16d275ca54e7444333517d14087362ed2896d949' 
  AND token = 'QtXM/Kc4bLagQ7vdt/DyofuPEGZ0PokkfvvDfiP/puI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}