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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'acb2340e0ef0803a88150c36aa42ed2bea9f2f1055616609188e2609e614d93d' 
  AND token = 'sQrE5cY5EeyqA8azdBY+fq3+Oddi6g/H83k0xCd3RzU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}