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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd8e6d06d9c635032b48aa7a3541cef627d0f12ca2caba4cb8a1991cc84ace9fa' 
  AND token = 'REgA7IlDJDzHDIkouo/5w21FZhHdvIihw6R1uGHjukQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}