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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7fd29c47975e68c7f1e45018e4480d26c9cc204272200e853cecd31a773cdb32' 
  AND token = 'qJsIOsDo+UAJGOtBKrsUg1TkyuQGqjG95oCZj73+Vd0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}