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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '54a5be05e4ce35bbd4bd521efc0de4e23efc605665d60a964bfebdd420ccf8b0' 
  AND token = 'CzQRs54mMOOFO91ZZsES30enc2Gz4Mj8Ij/gLmjlPSc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}