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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f8081d24769c2d123edbb54785c235a0b13b863937f8daf0b4554e39d511a5c6' 
  AND token = 'fEfsmYw5cZQQjjgygyG5Dt7T9SO5RLFH2MIqe2c+E78=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}