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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '265f9b5cc30bdbcf3fde5f93de214b2bcb7281bc04ab11d96f17a700574d9de1' 
  AND token = 't/9AgwkET7dxASkw94O4UQh8HSeNPdpTffVg1ZM3Kdo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}