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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3c6e1e9fefd9ae2f2bd097c05cce0c55734fd9afc7efc4e05c2c7266b4c61fc3' 
  AND token = 'ffd1+8fW49OFXgE8LUohTHLAYrksECtPF4lfMXvsj7s=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}