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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '75ceda6ba8807fdc38752a39a1bc54a17c9a71e30d31930c2b8d0b12e6cfd8bb' 
  AND token = '6U5sJa8kXVsIs635gj6lOqW7xgFk6Omy3ENzBzF7yTs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}