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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e6056ab451bb38c4069761007c6d0eb0428bc64d5363579a59ba8f3b8a463084' 
  AND token = 'PwBZtAK2PSTfix1C9PIYzzT+ourjeckoYWe14201Cv8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}