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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '403ac61b4b518fed9524f3c31d1865d3dec25210266260e980cdf4c0eed747ac' 
  AND token = 'ZarqdciZor5MHXAwBiH9VrdkkjHpvEgEqRT3gC4IIFM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}