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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ead22a87aee5e15183189b8ac7e5b4e46a0753bb07267a3d85c152b4275dc805' 
  AND token = 'TI5mwy3yK3kCDgQPyZBsxnzVDsua7v7gn/eJMQBP0NY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}