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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd1fb1015af4fefd6b95cd8b3279993a4da0ab66135dcbd21856433db200289ae' 
  AND token = 'AY+D3fx75/r4DCZyRANWCWFL4fQijClzc2nFacCzMYc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}