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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0cb035d78d99634bbde45b0c37d98af7e95fb0f068ac3547f49f008dc8c9f4d0' 
  AND token = 'wt6I02PSOh+l+kAPTg1Gw2YGKd/EUQxkmYSw6RYIuHA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}