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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3e4544c95e62ba7c044e3a6beb4a9375cd5ce7e8971ecfa7c71aa935603bb159' 
  AND token = 'LLyDGi1P54vrtxPC4iUoxT8IV4ztZKkcExgjwJbEC4U=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}