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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b63b551d84bfc1f2c943e281acafc7544a54ef626795cf9c284326013dae65c2' 
  AND token = 'jJyVFPjs1H2vrtpK4F75RF+UKq+Nr5Fp8CiHTaUKM1E=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}