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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3ca5d1b13d38e8599bb3e5f40957add1031cb56388e00cb8d9cd33706b0b16ac' 
  AND token = 'CXCL934+/QIE1wfZJoP0ArLmpwTqYYrWzePGu1penKg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}