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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a01767d1f506ac27d72e27606e191a8fc4bea9e5219946154ae69e253b28abc5' 
  AND token = 'ROIwFnteBGL9NItUa+I1F4jqScGTPhe9ANym0cmuOKM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00051

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}