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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '45d761ae4fc5028028864c9eade5eedf17bca9c8ab73c21998e218e8ef56d73c' 
  AND token = 'ucCMK/UA/GCW12h2wJbf+OO3NfeOSKONEdxSx1GzGSE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00048

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}