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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0e1a57e5ef4a583ceac8b1a4f00c99b7eff2cfd681c6ad035552909f90a83ddf' 
  AND token = '7t+EF4MhPjMdeev/TTCQ8JMPJaxcmQ8qjwUs1+qBJoA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}