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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cedad46960abfe3bc16dea5dd20b0c545e2323902762cf5a20615d3da6ee1d2e' 
  AND token = 'ofkLyg1FcHeOAH/3XK3CkA9C2aqY0Ez+T5kh60GGjG8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00045

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}