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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e4ac4219e0cbf90d53ca295cff7922cf0b44b94378fdeed93d65f42cdc3314fb' 
  AND token = '20/qdAL1PNTAGDbeWtfY0FMhDkIY6nDk1qloYj0oAdE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}