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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '60b5fa5fa5964cf0834f0fa6d7aa0f18576044b188449e7d68ed43a61460065b' 
  AND token = 'QBDUWW+kIxncTpmnYCSNyC1mskVkE5gfIW7caz7D07E=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}