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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '459026b6ad37f0c4019f549449806b66a5050012ff34c38b031577eb17af4e18' 
  AND token = 'RknlzTfI66bTK8af0nKWuuPBifg9HnQEtRpVLGBEF2o=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}