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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '462720022e4cbf891a296d0d8ef844360bc6094bc6a68c8cc6f25943d8aabedd' 
  AND token = 'AhuCEDtHBrBn9h2poMUy4GHew+KUyDUHsVyRZ9iLQT0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}