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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0cedb70f2d58ccb0adaaf98da25b37f8c512b667ddb8aa7336e768f325cf7dd0' 
  AND token = 'vNVYI6wXdB8P2NlIpWXqx9p3iTEpU4+ywE8ocSx0ewY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}