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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7ff81411ad5aa5671f0e150635e89a15636d2f19e16eb4cd4f6efd865ea11874' 
  AND token = '7uHgtTzjcz9Z6NScyREuwfB+QmmcnPlcBB/lj622PxQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}