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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '15c613667a483d177e930e8568b50d7e1af76b7d161da7fc100b6ef06fcbfbd8' 
  AND token = 'db38xa3IZjfx+DFP2yjIMPOUJL3TbGQDBBxZDFpEqmo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}