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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4e042442368606d51ab5818f11464680c74934d5b4830f3feb8e1543aa1d06aa' 
  AND token = 'hJWH21jKvSJHXk1MAslRBWSqXLdmK0I7WjjfMSjFQAM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}