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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a25fc9860a6477dcfc94e46c3af7b9c8dfb248ec46931547e350468d01263a78' 
  AND token = '0+WZV4c5RtFZF2K/3Lq2YFW5ZHiYhi0S2huAdSDw73Q=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}