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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2b2fc71dbe0f5e5e671ecef284900ea94c2fd1a7ac796ec982443b2a22588732' 
  AND token = 'Kcb2ajx80jG0tOK6PL4bbmeXz4NughZsXC0Bkficc5I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}