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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '61dfb5e5f13b620747c4aa92063cc19d47ff8842afbf07165da92dcdad5e212c' 
  AND token = 'zVQC02tlr9v8krk+vjkM6HLuDP1j3qL4iHALCJL58aA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}