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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f5df3a66cc0e2d4cec73d57ecbf64dc44e4fef475db4043629366655adeb0743' 
  AND token = '+Nj/qUuJ4r8g0g4Ap4UMHkX9umGnIVBPBqKErPCct0E=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}