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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4a5c7700b069c8eda39df4b76c5438741b09cde262156d2b46c7762f4f466ebe' 
  AND token = 'jWUw8+/9XoLngFqnaLoOEheKU0PHgk+VIwc0E055Ghg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}