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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b963b4f8faa6bb686aca78b57d605fbb492ed221f626f0fe4803d0fa1a466710' 
  AND token = 'xZbMU8TaWp0RauiW15R5u9lXGSzokVhedHusmzodALk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}