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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '37ad840e3c998cf00fc9c1f771db2c46c5cd4085fa2e55a63aba72a70019d530' 
  AND token = '8GYlrmhfE4GOhd3aPH1wORZzlTdwdr+KXrNq6gF3+eg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}