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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e2cfef82a1a931c7ddb640824f2ba44fdbceab5a3f67936eb963bcc7b1db79e1' 
  AND token = 'wkoVcESJjSS3b30gBzzIAu+APy+Wm+MWn8Pycz/djps=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}