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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '18ff0a2742454ba316492ad40aa268b61b321aa3a17d0e5c9a6b37684b1d3a1b' 
  AND token = 'AM9JO9EKkdOZgjqccSrORvKSvpWbAP4R/FR7j3GUEGo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}