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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8b41b72cb72777922ac21bd7f9c12612b89270a31e2b0bcefd0ae943f0511afb' 
  AND token = 'VPhD7/CpwvERtSH7qrD2CAZeoghnB1gujD6sQqkll/8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}